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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX12
All Species:
11.52
Human Site:
S571
Identified Species:
19.49
UniProt:
Q92771
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92771
NP_004391
950
106006
S571
L
A
A
P
A
D
E
S
Q
A
S
V
P
Q
P
Chimpanzee
Pan troglodytes
XP_520821
925
103112
S571
L
A
A
P
A
D
E
S
Q
A
S
T
P
R
P
Rhesus Macaque
Macaca mulatta
XP_001114477
931
104280
S552
P
A
A
P
A
D
E
S
Q
A
S
A
P
R
P
Dog
Lupus familis
XP_543872
907
102087
G553
P
V
T
P
V
E
D
G
E
A
R
V
P
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6AXC6
880
98710
E523
P
T
E
D
S
P
E
E
G
Q
A
V
A
L
R
Rat
Rattus norvegicus
XP_001070646
845
94905
M501
L
R
P
A
S
P
L
M
H
I
E
A
F
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517598
930
104705
G583
G
R
G
P
T
E
E
G
E
N
G
P
P
R
P
Chicken
Gallus gallus
XP_416375
940
105739
Q583
S
Y
K
E
G
P
L
Q
S
P
P
V
E
A
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007320
890
100643
S530
Q
S
K
P
T
D
V
S
E
Q
Q
M
A
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569898
861
96577
K526
Q
E
Q
Q
K
P
T
K
K
P
V
E
E
V
A
Honey Bee
Apis mellifera
XP_001121183
769
88327
M458
P
T
V
G
Q
S
I
M
K
F
L
L
L
N
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792082
780
88384
Q469
S
Q
C
S
L
R
F
Q
L
L
N
P
A
V
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22516
861
98787
T542
S
Q
F
L
Y
C
L
T
N
L
T
S
E
G
Q
Red Bread Mold
Neurospora crassa
A7UXD4
1073
119198
T657
H
T
L
C
S
F
L
T
A
L
T
N
L
S
S
Conservation
Percent
Protein Identity:
100
94.4
92.4
78.3
N.A.
72.3
67.7
N.A.
71.3
67.7
N.A.
57.2
N.A.
37.5
36.3
N.A.
45.4
Protein Similarity:
100
95.8
94.4
85.2
N.A.
80
76.2
N.A.
81.7
80.2
N.A.
73.4
N.A.
53.6
53.7
N.A.
61
P-Site Identity:
100
86.6
80
33.3
N.A.
13.3
6.6
N.A.
26.6
6.6
N.A.
20
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
93.3
86.6
60
N.A.
26.6
13.3
N.A.
46.6
6.6
N.A.
40
N.A.
6.6
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.2
25.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.5
43.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
22
22
8
22
0
0
0
8
29
8
15
22
8
8
% A
% Cys:
0
0
8
8
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
29
8
0
0
0
0
0
0
0
8
% D
% Glu:
0
8
8
8
0
15
36
8
22
0
8
8
22
0
15
% E
% Phe:
0
0
8
0
0
8
8
0
0
8
0
0
8
0
0
% F
% Gly:
8
0
8
8
8
0
0
15
8
0
8
0
0
8
0
% G
% His:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
15
0
8
0
0
8
15
0
0
0
0
0
0
% K
% Leu:
22
0
8
8
8
0
29
0
8
22
8
8
15
15
0
% L
% Met:
0
0
0
0
0
0
0
15
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
8
8
8
0
8
0
% N
% Pro:
29
0
8
43
0
29
0
0
0
15
8
15
36
0
43
% P
% Gln:
15
15
8
8
8
0
0
15
22
15
8
0
0
8
8
% Q
% Arg:
0
15
0
0
0
8
0
0
0
0
8
0
0
29
8
% R
% Ser:
22
8
0
8
22
8
0
29
8
0
22
8
0
8
8
% S
% Thr:
0
22
8
0
15
0
8
15
0
0
15
8
0
0
0
% T
% Val:
0
8
8
0
8
0
8
0
0
0
8
29
0
22
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _